initial intravenous dose of a long-acting parenteral antimicrobial such as 1 g of ceftriaxone or a consolidated 24-h dose of an aminoglycoside be administered first
Skin Blister Following multiple-dose administration every 12 hours for 5 days of 200 mg or 400 mg cefpodoxime proxetil, the mean maximum cefpodoxime concentration in skin blister fluid averaged 1
Renal impairment: Use with caution in patients with renal impairment; modify dosage in severe impairment
Duration of therapy: At least 10 days (Infections caused by Group A beta-hemolytic streptococci)
2 hours and urinary recovery averaged 21% after a 400 mg dose was given
The plasma levels reported from this study are as follows: 1 month or older: 5 to 7 mg/kg/day orally in 4 divided doses
Weight 22 to 30 kg: 37
In a study of 3 lactating women, levels of cefpodoxime in human milk were 0%, 2% and 6% of concomitant serum levels at 4 hours following a 200 mg oral dose of cefpodoxime proxetil
Creatinine clearance under 30 ml/min: give every 24 hours; Hemodialysis: give 3 times weekly after dialysis; cefpodoxime proxetil + methotrexate if oral methotrexate use, consider alternative or monitor CBC, renal fxn: combo may incr
Register; Hemodialysis: 500mg to 2 grams q24h, plus give a supplemental dose post-dialysis
It belongs to the class of medicines known as cephalosporin antibiotics
0 +/- 6
The bacteria that are susceptible to cefpodoxime include certain Staphylococcus and Pasteurella species, Streptococcus canis, E
In a study of 3 lactating women, levels of cefpodoxime in human milk were 0%, 2% and 6% of concomitant serum levels at 4 hours following a 200 mg oral dose of cefpodoxime proxetil
Cefpodoxime vs ciprofloxacin for short-course treatment of acute uncomplicated cystitis: a randomized trial
Infants and children 2 months to 12 years of age—Dose is based on body weight and must be determined by your doctor