This review article discusses the available evidence on quinolone allergy, including prevalence, risk factors, diagnosis, clinical manifestations, cross-reactivity, and management of allergic
cefalexin, has been reported to occur in up to 10% of patients
DRESS, and organ-specific reactions, there are few long- term antibiotic re-challenge or cross-reactivity data to guide future therapy
2% of non-SCAR delayed T cell mediated In immediate hypersensitivity, skin test results confirmed the diagnosis in 66 of 139 patients (47%)
Non-IgE-mediated hypersensitivity reactions Cross-reactivity among beta-lactam antibiotics with similar or identical side chains has been documented
Allergic reactions to macrolides are relatively less common compared to other classes of antibiotics (Figure 1)
Evidence suggests that there is an increased risk associated with the administration of a cephalosporin to an individual with a known penicillin allergy
Severe reactions include anaphylaxis, a life-threatening condition that
Of these cases, 2
When evaluated, fewer than 1% of the population are truly allergic to penicillins
The use of broad-spectrum antibiotics in patients labeled “penicillin Understanding Penicillin Allergy, Cross-reactivity, and Antibiotic Selection in the Preoperative Setting is an article published in the Journal of the American Academy of Orthopaedic Surgeons
Low-risk histories include patients having isolated nonallergic symptoms, such as Furthermore, cross-reactivity rates between different beta-lactam antibiotics are low, and patients with true penicillin allergy can still safely receive many cephalosporins and carbapenems [12-15]