As mentioned above, MAOIs can increase the risk of serotonin syndrome when combined with cyclobenzaprine
Go to: Evidence
Objective: To compare functional outcomes and pain at 1 week and 3 months after an ED visit for acute LBP among patients randomized to a 10-day course of (1)
Concomitant administration of cyclobenzaprine HCl and naproxen or diflunisal was well tolerated with no reported unexpected adverse effects
However combination therapy of cyclobenzaprine hydrochloride tablets with naproxen was associated with more side effects than therapy with naproxen alone
47 at 25°C
Taking cyclobenzaprine and gabapentin together may cause an increase in central nervous system (CNS) side effects
Can you combine back pain medications? Yes
Alcohol can increase the nervous system side effects of cyclobenzaprine such as dizziness, drowsiness, and difficulty concentrating
7 to 8
After taking a dose of cyclobenzaprine, you may start feeling tired or more relaxed within 30 minutes
Naproxen is ok as long as you're mindful of it's GI side effects (ulcers)
It is demonstrated that patients with muscle spasm associated with acute low back strain benefited from the use of combination therapy consisting of a nonsteroidal anti-inflammatory agent (naproxen) and a muscle relaxant (cyclobenzaprine)
You should avoid or limit the use of alcohol while being treated with
No well-controlled studies have been performed to indicate that cyclobenzaprine HCl enhances the clinical effect of aspirin or other analgesics, or
Call your doctor for medical advice about side effects
They found that neither naproxen combined with cyclobenzaprine nor naproxen combined with oxycodone and paracetamol provided better pain relief at
It will not prevent headaches or reduce the number of attacks
The combination of naproxen with skeletal muscle relaxants, such as orphenadrine or methocarbamol, is not superior to naproxen alone or placebo in patients with low back pain who are admitted to the
It has a melting point of 217oC, and a pK a of 8