Although the use of chloroquine (C) and hydroxychloroquine (HC) in the treatment of malaria prophylaxis during pregnancy is probably safe, the use of much higher doses for
The Centers for Disease Control and Prevention (CDC) now recommends the antimalarial drug mefloquine for pregnant women both as a malaria treatment option
Malaria infection in pregnant women can be more severe than in nonpregnant women and may also be transmitted from a mother to her unborn infant before or during delivery (“congenital” malaria)
One dose is taken beginning 2 weeks before traveling to an area where malaria is common, while you are in the Plaquenil is used to treat or prevent malaria and to treat the symptoms of rheumatoid arthritis
Benefit of use in prophylaxis and treatment in malaria outweighs risk
Begin 1-2 weeks before travel, once/week during travel, and for 4 Pregnant women should avoid travel to malaria-endemic areas if possible
It has also been used to treat COVID-19, Q fever, and Sjögren’s syndrome
Chloroquine is the antimalarial prophylaxis considered probably safe in pregnancy and hydroxychloroquine is generally recommended for pregnant patients with an autoimmune disease
Eight of these studies showed that women taking chloroquine did not have a higher chance of having a baby with a low birth weight (<2,500 g)
Hydroxychloroquine is a treatment for rheumatic disease and considered safe during pregnancy
In order to determine the pharmacokinetic disposition of chloroquine (CQ) and its active metabolite, desethylchloroquine (DECQ), when administered as intermittent presumptive treatment in pregnancy (IPTp) for malaria, 30 Papua New Guinean women in the second or third trimester of pregnancy and 30 age-matched nonpregnant women
They should take one dose per week while there, and for 4 consecutive weeks after leaving
Pregnancy Trimester, First
S