In this work, we evaluated combinations of linezolid with classic and new aminoglycosides (amikacin, gentamicin and plazomicin), carbapenems
Studies were identified by conducting PubMed and Embase searches using the following keywords in 1 or more combinations with “ Enterococcus faecalis ”: infective
Linezolid, an oxazolidinone antibiotic, is recommended for vancomycin-resistant enterococci (VRE)
The aim of this work is to evaluate and compare the effect of the use of tazocin (piperacillin-tazobactam)/vancomycin combination versus the use of tazocin/linezolid in the
The prevalence of VRE in China is relatively low, with a stable low resistance
We have previously demonstrated that the combination of cefepime with vancomycin, linezolid, or quinupristin-dalfopristin had an improved or enhanced effect against methicillin-resistant Staphylococcus aureus (MRSA)
Linezolid is a synthetic oxazolydinone active against multi-resistant Gram-positive cocci that inhibits proteins synthesis by interacting with the 50S ribosomal subunit
53 Among patients with vascular disease The combination of linezolid and rifampicin was shown to significantly reduce the incidence of anemia among patients with bone and joint infections compared to
The authors concluded that linezolid is not inferior to vancomycin
However, daptomycin is considered to be at least as effective as vancomycin in treating MRSA bacteremia, and a high dose of daptomycin is recommended in combination with
Our results indicate that vancomycin and linezolid in combination should be avoided
5 log 10 CFU/g) inocula of methicillin-susceptible and -resistant Staphylococcus aureus (MSSA and MRSA, respectively) on the activities of nafcillin, linezolid, vancomycin, and daptomycin, alone and in combination with gentamicin in an in vitro pharmacodynamic model with simulated
ness of linezolid in the treatment of MSSA toxic shock syndrome,17 no comparative data of the combination of linezolid with vancomycin in toxin-mediated clinical syn-dromes has been published
hospitalizations associated with VRE doubled between 2000 and 2006 and appear
Based on these data, combinations of linezolid with either daptomycin at 6 mg/kg or 10 mg/kg or vancomycin should be investigated for the clinical implications of in vitro
The activities of linezolid, an oxazolidinone antibacterial agent active against gram-positive organisms, alone and in combination with 35 antimicrobial agents were tested in vitro against methicillin-sensitive (n = 1 to 2 strains) and methicillin-resistant (n = 8 to 10) Staphylococcus aureus strains; vancomycin-sensitive (n = 6) and vancomycin-resistant
Combination of vancomycin and β-lactam therapy for methicillin-resistant Staphylococcus aureus bacteremia: a pilot multicenter randomized controlled trial
Combination of at least two antimicrobials is a possible strategy to obtain rapid and sustained bactericidal effects and overcome the emergence of resistance