Levodopa is in a class of medications called central nervous system agents
The oral dosage of L-DOPA with carbidopa (Sinemet) in Parkinson’s disease is usually 250 mg 2 to 4 times a day in the case of adults and teenagers
Adult: For intermittent treatment of episodic motor fluctuations (OFF episodes) in patients treated with levodopa/dopa-decarboxylase inhibitor (e
75 mg / 95 mg taken orally three times a day for the first 3 days
The usual; recommended starting dose is one tablet of carbidopa/levodopa 25/100 three times a day
The unscored, round, biconvex shaped tablets are brownish and debossed “S 50” on one side and plain on other side
If carbidopa and levodopa 10 mg/100 mg is used, dosage may be initiated with one tablet three or four
It should be noted that COMT inhibitors can lead to the amplification of levodopa-induced side effects, including dyskinesias, and it may be that
In fasted healthy volunteers the bioavailability of levodopa from INBRIJA was approximately 70% relative to immediate-release oral levodopa tablets
Patients converting from immediate-release formulation to controlled release: Initial: Dosage should be substituted at an amount that provides
However, this strategy can be counterproductive when the individual levodopa dose is high (ie, >200 mg) and may
tightness in the chest