Bupropion and naltrexone is a combination medicine used to help manage weight in obese or overweight adults with weight-related medical problems
Seizure disorder is a major
Your doctor will tell you not to take the combination of naltrexone and bupropion if you have taken or used opioids in at least the past 7 to 10 days
Effects of naltrexone/bupropion (NB) treatment on binge-eating frequency (A) and percentage weight loss (B) at posttreatment and 6-month follow-up (FU) (after treatment
Safety — Bupropion is
contraindications, or drug-drug interactions with bupropion or naltrexone
Naltrexone also modifies how the hypothalamus, pituitary gland and adrenal gland (hypothalamic-pituitary-adrenal axis, HPA axis) interact to suppress the amount of alcohol consumed
contraindications, or drug-drug interactions with bupropion or naltrexone
Naltrexone/bupropion (Contrave®), a combination of drugs with two different
Owing to the uncertainty about cardiovascular effects, we prefer to use GLP-1 receptor agonist therapy, combination phentermine-topiramate , or orlistat rather than bupropion
Bupropion, approved for
Naltrexone and its major metabolite, 6 β-naltrexol, are present in human milk; there are no data on bupropion, naltrexone, or their metabolites on milk production; the developmental and health benefits of feeling of warmth
Wellbutrin (bupropion) Wellbutrin XL (bupropion) Xanax (alprazolam) Zofran (ondansetron) Zoloft (sertraline) Zyrtec (cetirizine The maximum recommended daily dose of Contrave is two tablets taken twice daily (32 mg naltrexone hydrochloride and 360 mg bupropion hydrochloride), which is reached at the start of week 4
This medicine is used together with diet and exercise
Do not use naltrexone and bupropion combination if you are also using Zyban® to quit smoking or Aplenzin® or Wellbutrin® for depression, because they also contain bupropion
Seizure disorder or a history of seizures
However, CONTRAVE should not be taken with a high-fat meal because of a resulting significant increase in bupropion and naltrexone systemic exposure [see Warnings and Precautions (5
Contrave is a long-acting tablet that contains 8mg of naltrexone and 90mg of bupropion that is FDA approved for weight loss in people who are overweight or obese with at least one weight-related condition such as high blood pressure or type 2 diabetes