As an internal standard, 5-(4-methylphenyl)-5-phenylhydantoin was chosen; the extraction solvent from human urine was ether-chloroform (3:7)
• Overall, phenytoin resulted in an average (95% CI) AUC-fold reduction of 3
This impurity is a derivative of 5,5-diphenylimidazolidine-2,4-dione, which is the active
Phenytoin EP Impurity D (CAS No: 5157-15-3) Or Tetrahydro-3a,6a-diphenyl-imidazo
This page contains information about Phenytoin EP Impurity A
Phenytoin EP Impurity A Read more
Inv
However, as a result of N-nitrosamine impurity findings in marketed rifampin formulations, the application of rifampin in DDI studies has been halted
Sample COA & Data
The limit of detection was found to be 2
It is a yellowish-brown powder that is insoluble in water and soluble in organic solvents
1 It is important to note that N- nitrosamines are common and present in low levels in food, beverages, cosmetics, water, and to-bacco products 1
A new reversed-phase high-performance liquid chromatographic method with ultraviolet detection (RP-HPLC-UV) for simultaneous determination of phenytoin impurities, benzophenone and benzil, was This page contains information about Phenytoin EP Impurity D
This activity describes the indications, action, and contraindications for phenytoin as a valuable agent in the treatment of epilepsy
D J Grant,G G Zhang Int J Pharm
3 Diphenylhydantoic acid