hepatotoxicity
Updated May 13, 2022
Because ritonavir-boosted nirmatrelvir (brand name Paxlovid) is co-formulated with ritonavir as a pharmacologic booster, and ritonavir can alter levels of
By Dani Blum Jan
Side effects Before taking Dosage Overdose Interactions FAQ What is Paxlovid? Paxlovid (nirmatrelvir with ritonavir) is an antiviral medication used to treat
Interactions between Paxlovid and some cholesterol medications such as statins can be toxic to the liver, and interactions between Paxlovid and certain blood
Eating a high-fat meal did not significantly affect the blood levels of
By Laura Hegwer
Dan Barouch, director of the Center for Virology and Vaccine Research at Beth Israel Deaconess Medical Center in Paxlovid® and until one menstrual cycle after stopping Paxlovid®
Common interactions include atrioventricular block among females, and blood pressure decreased among males
This can increase the risk of side effects such as liver damage and a rare but serious condition called rhabdomyolysis that involves the breakdown of skeletal muscle tissue
Paxlovid is the first-choice treatment for mild to moderate COVID in people with a higher risk of severe illness
Because ritonavir-boosted nirmatrelvir (brand name Paxlovid) is co-formulated with ritonavir as a pharmacologic booster, and ritonavir can alter levels of many drugs, clinicians should be aware of and identify any potential drug interactions
Avoid combinations; the risk of the interaction outweighs the benefit
That way, they can let you know if any changes need to be made or if Paxlovid isn’t safe for
Risk of increased Paxlovid concentrations due to increased absorption from reduced first pass in the gut
But in some people, a side effect of Paxlovid is an unpleasant and lingering taste that develops in your mouth a day or two after beginning Find patient medical information for Paxlovid oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings
Early in your treatment with ritonavir, the interaction may be more unpredictable
Avoid combinations; the risk of the interaction outweighs the benefit
It is important you start treatment as soon as possible, within 5 days of symptom onset and testing positive for COVID