Losartan-induced angioedema is a rare side effect; however, because of the widespread use of this medication, it is vital for physicians to be aware of this rare
ARBs likely cause angioedema by upregulation of angiotensin type 2 receptors secondary to the blockage of angiotensin type 1 receptors
How it works Losartan may be used to treat high blood pressure or certain types of kidney disease
Edema, or the abnormal swelling of tissues caused by the accumulation of fluids, is a common side effect of calcium channel blockers, especially amlodipine
increased urination
More patients in the nifedipine group withdrew from the study as compared to the losartan/HCTZ group (19% vs 7%, p = 0
2 Reported rates of peripheral edema are dose-dependent, ranging from 5% to 70% with a high dose
e
Ways to reduce swelling from amlodipine include: Non-pharmacological interventions, such as using a footstool to raise your legs as often as possible; regularly doing foot exercises to promote better movement and circulation
Blurred vision ANGIOEDEMA, or angioneurotic edema (Quincke edema), is a well-demarcated, nonpitting edema of the skin and subcutis
Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
9 This is believed to be the result of red blood cell leakage from capillaries and can cause a long‐lasting discoloration
ankles
Life expectancy
and meta-analyses
Angiotensin receptor blockers (ARBs) selectively block the binding of angiotensin II to the angiotensin type 1 receptor
tightness in the chest
Arch Intern Med
Americal Journal of Therapeutics 2009; 16(6): 543-553; The present cohort study reported by Scott Martin Vouri et al
Venlafaxine is in a different class called SNRI's and it only causes edema in rare cases