Based on the entire pH range of 1
Montelukast sodium, mixed with either HFA 134a propellant or a mixed propellant (HFA-134a and HFA227), was formulated into a pMDI with other excipients
It contains a montelukast (1-)
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Montelukast is an orally dosed drug (available as a film-coated tablet, chewable tablet, or oral granules) that is FDA-approved for treating chronic asthma and prophylaxis and the prevention of exercise
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solubility of pyrimethamine and metronidazole, allowing us to classify the solubility according to the Biopharmaceutics Classification System (BCS)
montelukast sodium and levocetirizine dihydrochloride combinations are offered in the form of syrups; however, montelukast, being a BCS class II molecule, exhibits low solubility and high permeability4
5 μg/mL and 150–450 μg/mL for Montelukast Sodium and Fexofenadine hydrochloride with correlation coefficient greater than 0
Montelukast sodium is a lipophilic drug; hence, using solubilizing agents such as bile salts in FaSSIF media improve its solubility
Montelukast is used to treat and prevent asthma
It is also approved to relieve seasonal and perennial allergic rhinitis symptoms
The formulation GMTFCS-4 shows 29
ChEBI: Montelukast sodium is an organic sodium salt
As montelukast belongs to BCS class II, the osmotically controlled pulsatile delivery system will be a suitable device to release the drug in slightly controlled manner to overcome the problem of saturation solubility in gastro-intestinal (GI) tract
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It is used for prophylaxis and treatment of asthma and allergic rhinitis by oral administration
For allergic rhinitis it is a second-line treatment
Two formulations of each drug were Uses of Montelukast Oral Granules: It is used to ease allergy signs