10125807
~10-12 hours after the last dose) When to get a level This medicine works by killing the fungus or yeast, or preventing its growth
There is an inverse relationship between the elimination half-life and creatinine clearance
Oral: Oropharyngeal candidiasis: 200mg orally x 1, followed by 100mg orally once daily
Fluconazole IV/PO 400 mg q24h for CNS) Disseminated infections LD 800 mg LD x1, then 400 mg q24h (up to 800 - 1200 mg q24h for CNS) LD 800 mg x1, then = Renal Dosing Guidance Updated Back to TopOctober 2023 Medication Indications & Comments Usual Dose CrCl >50 mL/min CrCl 31-50 mL/min CrCl 10-30 mL/min CrCl < 10 mL/min Anephric/HD* First dose
Children younger than 6 months of age—Use and dose must be determined by your doctor
CAPD
[PMID: 7579091] / Kishino S, Koshinami Y, Hosoi T, Suda N, Takekuma Y Dosing recommendations for individual drugs can be found in Drug Prescribing in Renal Failure: Dosing Guidelines for Adults
The recommended duration of treatment for initial therapy of cryptococcal meningitis is 10 to 12 weeks after the cerebrospinal fluid becomes culture negative
CVVHD
1093/NDT/GFG363 Corpus ID: 1991676; Dosing guidelines for fluconazole in patients with renal failure
Brand name: Dosage In Patients With Impaired Renal Function: Fluconazole is cleared primarily by renal excretion as unchanged drug
See more Dosage In Patients With Impaired Renal Function: Fluconazole is cleared primarily by renal excretion as unchanged drug
In patients whose
100–200 mg thrice a week after each haemodialysis session
Supplement For Dialysis [Recommendation Level]: Crrt
The dose is usually 6 milligrams (mg) per kilogram (kg) of body weight on the first day, followed by 3 mg per kg of body weight once a day, for at least 2 weeks
124 mL/min/kg) for the elderly were generally lower than those of younger volunteers
CVVHD
Drug dosage is based on the type and severity of infection, identity of the causative organism
100–200 mg every 24 h (depending on plasma concentrations) 800 mg
The dose of fluconazole may need to be reduced in patients with impaired renal function
Renal impairment
400 mg IV/PO q24h
For patients with renal failure, a reduction of the fluconazole maintenance dose is necessary because of delayed elimination
Dosage in Patients With Impaired Renal Function
27
Treatment should be continued until clinical parameters or laboratory tests indicate that active fungal infection has subsided
Dosage In Patients With Impaired Renal Function
Fluconazole capsules can be sold to the public for vaginal candidiasis and associated candidal balanitis in those aged 16–60 years, in a container or packaging containing not more Since candidemia is associated with increased cost and mortality, the dose of fluconazole in patients at risk for developing candidemia should be 6- to 12-mg/kg daily (400-800 mg daily)
Therefore standard-dose trimethoprim-sulfamethoxazole in data (when available), and residual renal function
Dosage adjustment of fluconazole during continuous renal replacement therapy (CAVH, CVVH, CAVHD, CVVHD)
Adults—Doses of up to 400 milligrams (mg) per day
Diflucan is a medication used to treat fungal infections in kids and adults
There is an inverse relationship between the elimination half-life and creatinine clearance
Max for all: 600mg/day