x, 28:12, (1101-1105), Online publication date: 1-Dec-1988
Propranolol is a beta-adrenergic receptor antagonist used to treat hypertension
Pharm 101: Propranolol Robert Buttner Jul 19, 2020 Home Basic Science Pharmacology Top 200 Drugs Class Beta-blocker Class II antiarrhythmic
hawthorn increases effects of propranolol by pharmacodynamic synergism
Boudoulas H, Beaver B, Kates R and Lewis R (1978) Pharmacodynamics of Inotropic and Chronotropic Responses to Oral Therapy with Propranolol, Chest
Propranolol is a substrate of CYP2D6, CYP1A2 and CYP2C19, retaining potential pharmacokinetic interactions with co-administered drugs
Propranolol is used to treat tremors, angina (chest pain), hypertension (high blood pressure), heart rhythm disorders, and other heart or circulatory conditions
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Each subject received 160
The primary treatment option for pheochromocytoma, which is a catecholamine-secreting tumor of the adrenal gland, is surgical resection
Propranolol did not have an effect on the pharmacokinetics of fluvastatin
The pharmacokinetics of propranolol have not been investigated in patients under 18 years of age
The time of Cmax was significantly later with LA propranolol in both phases
Age, gender, race and ethnicity do not alter its pharmacokinetics
A comprehensive literature search was done by using Pubmed and Google Scholar databases to shortlist the published literature in which concentration-time profiles and pharmacokinetic data of propranolol were available after oral and IV administration
Outpatient prescriptions may include once-a-day dosing for longer-acting beta-blockers, such as metoprolol succinate
A total of 43 subjects were allocated into three study groups: (1) healthy, lean, normolipaemic volunteers, (2) obese normolipaemic subjects, and (3) obese Propranolol is a racemic mixture of 2 enantiomers where the S (-)-enantiomer has approximately 100 times the binding affinity for beta adrenergic receptors
(14)C-labelled propranolol was given either intravenously or by mouth and the disappearance rates of propranolol, 4-hydroxypropranolol, and total radioactive metabolites measured
The duration and extent of cardiac beta-blockade and their relationship to propranolol pharmacokinetics were assessed in nine healthy volunteers
Propranolol: Total Clearance: 65
Elimination occurs almost wholly by metabolic transformation in the liver and excretion of the resultant products in the urine
Albuterol is a commonly prescribed bronchodilator used for managing diverse respiratory
Each mL contains 1 mg of propranolol hydrochloride in Water for Injection
These data indicate that propranolol exerts mechanism‐based inhibition of hepatic CYP2D in vitro and in vivo in TG and WT mice, and that this inhibition is sufficient to alter drug‐induced behaviour (catalepsy)