Cefuroxime injection is also available as a premixed product to be injected intravenously
5 g, serum concentrations were approximately 50 and 100 mcg/mL, respectively, at 15 minutes
The pH has been adjusted with hydrochloric acid and may have been adjusted with sodium hydroxide
Intravenous administration Dissolve the powder in water for injections using at least 2ml for 250mg cefuroxime, at least 6ml for 750mg cefuroxime or 15ml for 1
6 to 45
fast heartbeat hives or welts increased thirst muscle spasm or jerking of all extremities nausea or vomiting skin itching, rash, or redness sudden loss of
After intramuscular (IM) injection of a 750-mg dose of cefuroxime to normal volunteers, the mean peak serum concentration was 27 mcg/mL
5 g bulk package not to be used for direct injection
DESCRIPTION Cefuroxime for Injection, USP is a sterile semisynthetic, broad-spectrum, cephalosporin antibiotic for parenteral administration
Patients Dose Number of Patients Mean (Range) CSF Cefuroxime Concentrations (mcg/mL) Achieved Within 8 Hours Post Dose Pediatric patients (4 weeks to 6
5 g; 250
Cefuroxime injection is to be given intravenously (into the vein) or intramuscularly (into the muscle)
When the 750 mg and 1
ORAL:3 months to 12 years: Oral suspension: 10 to 15 mg/kg orally twice a day
After intramuscular (IM) injection of cefuroxime to normal volunteers, the mean peak serum concentrations ranged from 27 to 35 µg/mL for a 750 mg dose and from 33 to 40 µg/mL for a 1000 mg dose, and were achieved within 30 to 60 minutes after administration
After intramuscular (IM) injection of a 750 mg dose of cefuroxime to normal volunteers, the mean peak serum concentration was 27 mcg/mL
Approximately 89% of a dose of cefuroxime is excreted by the kidneys over an 8-hour period, resulting in high urinary concentrations
5 g, serum concentrations were approximately 50 and 100 mcg/mL, respectively, at 15 minutes
Cefuroxime injection is sometimes given before and after a surgery to prevent infection
After intramuscular (IM) injection of cefuroxime to normal volunteers, the mean peak serum concentrations ranged from 27 to 35 µg/mL for a 750 mg dose and from 33 to 40 µg/mL for a 1000 mg dose, and were achieved within 30 to 60 minutes after administration
1975; 18:711–9
0 per cent
Following intravenous (IV) doses of 750 and 1500 mg, serum concentrations were After intramuscular (IM) injection of cefuroxime to normal volunteers, the mean peak serum concentrations ranged from 27 to 35 µg/mL for a 750 mg dose and from 33 to 40 µg/mL for a 1000 mg dose, and were achieved within 30 to 60 minutes after administration
Teenagers with certain bacterial infections, The importance of perioperative prophylaxis with cefuroxime or ceftriaxone in the surgical site infections prevention after cranial and spinal neurosurgical procedures
After intramuscular (IM) injection of a 750-mg dose of cefuroxime to normal volunteers, the mean peak serum concentration was 27 mcg/mL
Some side effects may occur that usually do not need medical attention
5 g 8 hourly via deep IM inj or IV inj over 3-5 minutes or infused over 30-60 minutes
Intramuscular, Intravenous