Oct 26, 2017 · Commonly used thiazide diuretics include chlorthalidone, hydrochlorothiazide, indapamide and metolazone
Inclusion criteria were as follows: (a) patients with hypertension; (b) use in the diuretic arm of HCTZ, chlorthalidone, indapamide, triamterene/HCTZ, amiloride/HCTZ, spironolactone/HCTZ, spironolactone, eplerenone, or canrenone; (c) use in its comparator arm of another diuretic or one of the nondiuretic classes commonly used to Diuretics are generally safe
See more Indapamide has proven antihypertensive efficacy among those with
The landmark PATHWAY-2 study demonstrated a major benefit of spironolactone in treating patients with RHTN uncontrolled on a standardized 3-drug regimen of an ACE inhibitor or ARB, amlodipine
PATHWAY-2
5 mg tablets in all but 1 trial, provided a 54%
After a 2-week run-in period on amlodipine 5mg once daily, patients who
Anuria
Indapamide is a thiazide-type diuretic derived from chlorosulphonamide
Aldactone also is used to counteract the effects of excessive
To compare continuous data (e
Thiazide-like diuretics (indapamide and chlorthalidone) have shown similar effectiveness
Spironolactone/HCTZ (Aldactazide) 25 mg/25 mg: $17 ($85) 50 mg/50 mg et al
The aims of the current review were to compare the efficacy of monotherapy with bendroflumethiazide vs
If a person is already taking a conventional thiazide diuretic such as Descriptions
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22% of reviewers reported a positive effect, while 39% reported a negative Despite this, the most frequent diuretic used in clinical practice as add-on therapy for hypertension is HCTZ
7 to −1
Loop diuretics serve two main purposes, to maintain euvolemia for chronic HF patients and to achieve decongestion in ADHF patients [ 4, 5 ]
Indapamide (GREY) is a 2nd line option
5mg for hypertension – higher doses only increase the incidence of metabolic and other side effects
Monitor renal function and sodium and potassium within a month of commencing treatment and repeat as needed
Potassium vs Salt
Both Indapamide and Aripiprazole can increase the risk of hyponatraemia