falciparum predominates in Africa, it is found in combination with chloroquine-sensitive P
Although chloroquine-resistant P
Key Information Needed and Helpful Links to Assess Need for Prophylaxis for Select Countries
falciparum 20%
, 2006)
falciparum predominates in Africa, it is found in combination with chloroquine-sensitive P
It is available in tablets of two sizes: 150mg base (250mg salt) and 300mg base (500mg salt)
Since then, chloroquine resistance has spread to nearly all areas of the world where falciparum malaria is transmitted
• Antimalarials available on prescription in Canada include chloroquine (or hydroxychloroquine), atovaquone-proguanil, doxycycline, mefloquine and primaquine
1 Some estimates place its total mortality burden at one-half of all people who have ever lived
P vivax and P ovale require additional therapy with an 8-aminoquinoline to eradicate the liver stage For severe malaria, intravenous artesunate is first-line therapy
Number of studies: Database last updated: Read Story Invasive vector species CS237187-A The weekly dosage for adults is 300mg base (500mg salt)
It should be started 1 week before entering an endemic area, continued Chloroquine is a medication used in the management and treatment of malaria and inflammatory diseases
falciparum or Species Not Identified - Acquired in Areas With Chloroquine Resistance The return of chloroquine-sensitive Plasmodium falciparum in sub-Saharan Africa countries offers the opportunity for the reintroduction of chloroquine (CQ) either in combination with other drugs or as a single therapy for the management of malaria
Worldwide there are over 30 Background Pfcrt gene has been associated with chloroquine resistance and the pfmdr1 gene can alter malaria parasite susceptibility to lumefantrine, mefloquine, and chloroquine
In Zambia, chloroquine was used as treatment for uncomplicated malaria for a long time until Pf Malaria microscopy EQA
knowlesi-positive, 1 mixed positive of P
vivax-positive slide (63 p/µL) was Travel to Areas with Chloroquine-Resistant Malaria
vivax malaria in South America and Asia
Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA
1086/322858
falciparum predominates in Africa, it is found in combination with chloroquine-sensitive P
Afghanistan
Although chloroquine-resistant P
Methods Chloroquine is a medication primarily used to prevent and treat malaria in areas where malaria remains sensitive to its effects
vivax 85%, P
Although chloroquine-resistant P
falciparum predominates in Africa, it is found in combination with chloroquine-sensitive P
falciparum is found in all parts of the world except the Caribbean and countries west of the Panama Canal
These sweeps presumably occurred as a result of intense chloroquine pressure
Other areas with malaria: None (mosquito There is a significant change in the proportions of the resistant genotypes in the endemic areas while in the epidemics, there was also a noticeable shift though not significant, which indicates a slow but steady re-emergence of P
falciparum and works by inhibiting parasite growth by concentrating within the parasite acid vesicles, thereby raising internal pH
vivax, P
Areas with Chloroquine-sensitive Malaria
Other areas with malaria: None (mosquito avoidance only) 6: Department(s) of travel Map of departments of Nicaragua external icon
The limit of microscopy detection is approximately 50 parasites/uL
falciparum is found in all parts of the world except the Caribbean and countries west of the Panama Canal
In a 2,000-sq km region, mosquitoes were collected from human sleeping rooms using pyrethrum spray catches during the 2006 malaria transmission season
falciparum predominates in Africa, it is found in combination with chloroquine-sensitive P
vivax 60%; P
falciparum is found in all parts of the world except the Caribbean and countries west of the Panama Canal
Introduction
malariae in tropical areas such as Latin America, the Indian Travel to Areas with Chloroquine-Resistant Malaria
vivax malaria in South America and Asia
falciparum predominates in Africa, it is found in combination with chloroquine-sensitive P
Although chloroquine-resistant P
falciparum is found in all parts of the world except the Caribbean and countries west of the Panama Canal
falciparum, e
falciparum is found in all parts of the world except the Caribbean and countries west of the Panama Canal
Chloroquine-resistant P
vivax malaria in South America and Asia
falciparum predominates in Africa, it is found in combination with chloroquine-sensitive P
vivax malaria in South America and Asia
falciparum predominates in Africa, it is found in combination with chloroquine-sensitive P
falciparum is found in all parts of the world except the Caribbean and countries west of the Panama Canal
5
1 Some estimates place its total mortality burden at one-half of all people who have ever lived
Antimalarials available on prescription in Canada include chloroquine (or
Background Plasmodium falciparum ( Pf) resistance to anti-malarial drugs remains a
Rare cases in other provinces in areas <1,500m (4,921 ft)
The limit of microscopy detection is approximately 50 parasites/uL
Chloroquine (also known as chloroquine phosphate) is an antimalarial medicine
Treatment of mild malaria due to a chloroquine-resistant parasite consists of a combination therapy that includes artemisinin or chloroquine for chloroquine-sensitive malaria
Travel to Areas with Chloroquine-Resistant Malaria
falciparum predominates in Africa, it is found in combination with chloroquine-sensitive P
Less commonly, P
falciparum is found in all parts of the world except the Caribbean and countries west of the Panama Canal
The reintroduction of chloroquine, ideally in combination with another antimalarial drug, should be considered in areas where chloroquine resistance has declined and safe and
falciparum predominates in Africa, it is found in combination with chloroquine-sensitive P
Chloroquine or Hydroxychloroquine
vivax : Atovaquone-proguanil, doxycycline All travelers should seek medical attention in the event of fever during or after return from travel to areas with malaria
These include Areas with chloroquine-sensitive malaria include many Latin American countries where there is predominantly P
Chloroquine-resistant P
vivax malaria in South America and Asia
falciparum predominates in Africa, it is found in combination with chloroquine-sensitive P
Chloroquine-resistant P
Chloroquine (CQ), a protonated, weakly basic drug, exerts its antimalarial effect mainly by increasing pH and accumulating in the food vacuole of the parasites
But in many parts of the world, parasites are resistant to chloroquine, and the drug is no longer an effective treatment