, Peak Body Stores) x % Daily Loss/100 (% Daily Loss = 14 + Creatinine clearance/5) Reduce the dose of LANOXIN in patients whose lean weight is an abnormally small fraction of their total body mass because of obesity or edema
Geriatric Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of digoxin in the elderly
For maximal early benefits in treating tachyarrhythmias, digoxin requires loading doses, which can be administered intravenously or orally
How should I give it? Give digoxin at regular times (either once a day or every 12 hours) to keep a steady level in the bloodstream, and to make sure you remember to give it
> 10 years or weight >30 kg§
Infants 1 month to 24 months of age—Dose is based on age, body weight, and medical condition and must be determined by your doctor
Greater than 10 to less than 18 years: IV: 8 to 12 mcg/kg; Oral solution: 10 to 15 mcg/kg; Tablets: 10 to 15 mcg/kg
Lanoxin (digoxin) dosing, indications, interactions, adverse effects, and more Avoid in patients with myocarditis Risk of advanced or complete heart block in patients with sinus
But only 6% of pediatricians do, according to survey results
Serious side effects may be more likely in older adults and those who are ill or
O and IV: VLBW digitalising dose: 10 microgram/kg following at 8 hourly intervals by 5 mcg/kg for 2 doses
The pediatric elixir comes with a specially marked dropper for measuring the dose
However, it is not known whether such high concentrations are necessary for Based on data from 2 lactation studies in a total of 13 breastfed infants, digoxin concentrations in breast milk ranged between 0
-If this drug is used during pregnancy, neonates should be monitored for signs and symptoms of toxicity (e
or
This translates to relative infant dose of digoxin between 1 to 7% of maternal weight- adjusted dose and about 0
Pharmacology, adverse reactions, warnings and side effects
You may
2 to 4% of the neonatal maintenance dose
For children: This drug hasn’t been established as The digoxin dose received through breastfeeding is up to 4% of the neonatal maintenance dosage, which is unlikely to be clinically relevant
However, infants are more likely to be very sensitive to the effects of digoxin which may require an individual dose for infants receiving digoxin
Discuss Digoxin (Oral Route) It is very important that your doctor check your progress closely while you are using this medicine to see if it is working properly and to allow for a change in the dose
nausea, diarrhea; feeling weak or dizzy; headache, weakness, anxiety Clark’s rule for pediatric dosage is based on proportional body weights as related to the standard weight mean of 150 pounds
08% anhydrous citric acid
Most people take it in the morning after breakfast
Digoxin should be diluted 4 times or more in volume of selected appropriate diluent (e
Avoid administration in the presence of precipitate in the vial or ampule
(3) Premature and immature newborns display considerable variability in their tolerance to digoxin; hence, the dosage of the drug must be individualized according to their degree of maturity
However, elderly patients are
Therefore, this amount should have no pharmacologic effect upon the infant
25-mg) tablets for oral administration
The safety and effectiveness of Digoxin Tablets in the control of ventricular rate in children with atrial fibrillation have not been established