In 2010, CDC recommended a single 250 mg intramuscular (IM) dose of ceftriaxone and a single 1 g oral dose of azithromycin for treatment of uncomplicated gonococcal infections of the cervix, urethra, and rectum as a strategy for preventing ceftriaxone resistance and treating possible coinfection with Chlamydia trachomatis ( 4 )
Seizures
The dose of azithromycin chosen was combined with a subprotective dose of ceftriaxone in the CLP-induced sepsis model, and the survival benefit and immunomodulatory activity were assessed
Typically, the dosage ranges from 5 to 20 mg per kilogram of body weight once daily for three to five days
So what can you do? participants received either a single dose of intramuscular ceftriaxone 500 mg, intramuscular ertapenem 1,000 mg, intramuscular gentamycin at 5 mg/kg, or Ceftriaxone remains the primary treatment for gonorrheal infection, but it now warrants a single 500-mg intramuscular dose or a 1-g intramuscular dose for patients weighing 331 lb (150 kg) or more
Azithromycin is an antibiotic used to treat a variety of different infections
0 g orally, and ceftriaxone, 250 mg intramuscularly
See Pediatric Antimicrobial Dosing Guidelines
CDC recommends that single-dose azithromycin or ceftriaxone regimens be used in HIV patients only if follow-up can be ensured
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1 mg/kg IV q24h CrCl 25-50: Same dose q12h CrCl 10-24: Same dose q24h CrCl <10: 5-6
The three first-line oral antibiotics for Lyme disease include doxycycline (Monodox, Doryx, Vibramycin, Oracea), amoxicillin (Amoxil), and cefuroxime (Ceftin, Zinacef)
Rosuvastatin (Crestor) 5 to 40 mg daily
Azithromycin Dose Pack, Z-Pak, Zithromax: Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value
250 mg; 500 mg ceftriaxone 250 mg intramuscularly (IM) once plus azithromycin 1 g orally once (preferred) or alternatively, doxycycline 100 mg orally every 12 hours for 7 days
In adults: Ceftriaxone is used for Lyme disease affecting the central nervous system, A but the dose is not licensed for this indication
For children weighing ≥45 kg but aged <8 years: Azithromycin 1 g orally in a single dose
Community-acquired pneumonia (CAP) is defined as an acute infection of the pulmonary parenchyma in a patient who has acquired the infection in the community, as distinguished from hospital-acquired (nosocomial) pneumonia (HAP)
Dyspnea increases
After a 1 gm IV dose, average concentrations of ceftriaxone, determined from 1 to 3 hours after dosing, were 581 μg/mL in the 7 mg per kg per dose three times daily (maximum = 300 mg per dose) 10 days: Strong, moderate: Azithromycin (Zithromax), oral Ceftriaxone (Rocephin), 1 to 2 g IV every day PLUS Azithromycin (Zithromax), 500 mg orally or IV every day or Clarithromycin (Biaxin), 500 mg orally every 12 hours OR During pregnancy, azithromycin 1 g as a single dose is recommended to treat chlamydia
Pregnant women can be treated with ceftriaxone 500 mg similar to nonpregnant patients with gonococcal infections
Medically reviewed by Drugs
Azithromycin 10 mg/kg/dose (max 500 mg/dose) enterally daily OR Ceftriaxone* 50 mg/kg/dose (max 1000 mg/dose) IV q24h *For infants 1-3 months of age and if needed
azithromycin 2 gm orally in a single dose If ceftriaxone administration is not available or not feasible: 17cefixime 800 mg orally in a single dose Uncomplicated infections of the