This medication is usually used at a later stage of Parkinson's disease and in combination with Sinemet®
Available as
The first monoamine oxidase (MAO-B) inhibitor for PD, selegiline (Eldepryl), was approved by the Food and Drug Administration (FDA) in 1996, and rasagiline (Azilect) received
Selegiline (brand names: Eldepryl, Emsam, Zelapar), rasagiline (brand name: Azilect), and safinamide (brand name: Xadago) are monoamine oxidase type B
Selegiline—available as Eldepryl capsules (Somerset Pharmaceuticals), Zelapar orally disintegrating tablets (ODTs, Valeant Pharmaceuticals International), and numerous
Rasagiline (Azilect) is a highly selective and potent propargylamine inhibitor of monoamine oxidase (MAO) type B
Rasagiline (N-propargyl-[1R]-aminoindan) (Azilect, Teva Pharmaceutical Industries) is an inhibitor of monoamine oxidase type B (MAO-B) that is approved for the
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The largest, a retrospective
Selegiline is available under the following different brand names: Eldepryl and Zelapar
5,7–11 The time interval between the commencement of rasagiline or selegiline treatment as the first antiparkinsonian drug (APD) and the initiation Summary
unsteadiness, trembling, or other problems with muscle control or coordination
It is commonly referred to in the clinical and pharmacological literature as l-deprenyl
Your doctor may start you on a low dose of transdermal selegiline and gradually increase your dose, not more often than once every 2 weeks
S
It is a conjugate base of a (-)-selegiline (1+)
(Nardil), selegiline (Eldepryl Rasagiline (Azilect, Azipron) is an irreversible inhibitor of monoamine oxidase-B used as a monotherapy to treat symptoms in early Parkinson's disease or as an adjunct therapy in more advanced cases
5 mg
Previous literature is limited to uncontrolled data and focuses on selegiline rather than rasagiline
20, 34, 35 Rasagiline possesses a
It is commonly referred to in the clinical and pharmacological literature as 1-deprenyl
Selegiline is rapidly distributed throughout the body, the apparent volume of distribution being 500 1 after an intravenous 10 mg dose
The effect of selegiline and rasagiline was not analyzed separately
Tell your doctor about all medicines you have used in the 2-week period before you start taking Description and Brand Names