The mechanism for this property of
This is a partial list of medications that may increase or decrease warfarin effect on the INR
John's wort, carbamazepine, and the polycyclic aromatic carbons in
Warfarin is used to treat or prevent blood clots in veins or arteries, which
A second group received trazodone, an older antidepressant drug that is widely prescribed off-label for insomnia due to its sedative effects
Vitamin K
Warfarin may also be used for purposes not listed in this medication guide
Drug and food interactions are frequently cited as causes of adverse events with warfarin
, deep venous thrombosis, pulmonary embolism, prophylaxis against coronary artery thrombosis following acute myocardial infarction, prophylaxis against cardioembolic stroke in patients with atrial
Psychotropics that may significantly decrease the INR when used with warfarin include trazodone, St
The use of trazodone on an as-needed basis for sleep is strongly discouraged in patients who are receiving warfarin, due to the difficulty of achieving a therapeutic PT and INR
Warfarin (Coumadin): using trazodone with this drug can lead to difficulties with blood clotting
2% of the patients who use the anticoagulant, and at least one drug that interacts with it (2)
Antidepressants (ADs) are frequently used in the treatment of depression, anxiety disorders, and several other mental disorders (1–4)
Trazodone hydrochloride has active ingredients of trazodone hydrochloride
Currently, eHealthMe is studying from 132,601 Coumadin users
Paxlovid can make bupropion levels go down, potentially making it less effective
Antidepressants
Does Coumadin interact with my other drugs? Enter other medications to view a detailed report
There have been reports of altered (either increased or decreased) prothrombin times in taking both warfarin and