The synthesis of Loperamide Hydrochloride followed the synthesis of diphenoxylate hydrochloride as an antidiarrheal with fewer opiates, similar to the central
8 It decreases peristalsis and fluid secretion in the gastrointestinal tract, delays colonic
(A) Differential scanning calorimetry (DSC) of loperamide HCl, mannitol and physical mixture; (B) DSC of loperamide HCl, magnesium stearate and physical mixture;
It works by slowing down the
Introductiontonon-linearproblems 114 1
This allows not
Initial Dosage of Loperamide Hydrochloride for Children 2–12 Years of Age108
The samples containing 20% loperamide were stored under different conditions (40 °C and 0% RH, 25 °C and 52% RH, 4 °C and 0% RH) to investigate their stability as a function of time
Questions or comments? Call 1-877-895-3665 (toll-free) or 215-273-8755 (collect) Imodium A-D should not be given to a child younger than 2 years old
Visit ChemicalBook To find more Loperamide hydrochloride(34552-83-5) information like chemical properties,Structure,melting point,boiling point,density,molecular formula,molecular weight, physical properties,toxicity information,customs codes
Max: 16 mg daily
Coadministration with other CNS depressants, such as skeletal muscle relaxants, may cause respiratory depression, hypotension, profound sedation, coma, and/or death
Individuals with a short bowel or a high stoma output are more likely to have a faster bowel transit of
FIGURE 4
80% of reviewers reported a positive effect, while 11% reported a negative effect
Loperamide is an anti-diarrhoeal medication
IMODIUM ORIGINAL 2mg capsules
Medically reviewed by Drugs
Imodium is a brand-name drug that’s prescribed for acute (short-term) and chronic (ongoing) diarrhea
In vitro loperamide is metabolized mainly by cytochrome P450 (CYP450) isozymes, CYP2C8 and CYP3A4, to form- N-demethyl loperamide