Pulmonary toxicity due to nitrofurantoin has two main presentations: an acute onset approximately nine days after a short course of therapy and a chronic onset
Background Nitrofurantoin is an antimicrobial drug recommended as the first-line treatment for uncomplicated cystitis, urinary tract infection (UTI) and prophylaxis for recurrent UTI
This website requires cookies, and the limited processing of your personal data in order to function
This result section includes data primarily on lung toxicity as it is the most commonly involved
Potential adverse effects include pulmonary toxicity, hepatitis, cholestasis, peripheral neuropathy and aplastic anaemia
Pulmonary reaction secondary to nitrofurantoin is a potentially serious, even fatal, adverse drug reaction
Common adverse effects are nausea and vomiting, which are less likely with the macrocrystalline form
Nitrofurantoin is a well-known antibacterial agent used in treating urinary tract infections (UTIs), particularly acute uncomplicated cystitis, and is also used in prophylaxis for patients with recurrent UTIs [1,2]
1 Although these complications are rare, it is important to recognize them because they can be potentially serious and even fatal
Nitrofurantoin lung toxicity was diagnosed among ten patients receiving 50 mg/day to prevent recurrent urinary tract infection
All but one patient, with irreversible lung injury at presentation recovered completely, five after drug discontinuation and four after steroids therapy
In six patients a symptomatic period of 3-36 months preceded the diagnosis
2 However, pulmonary adverse reactions are Nitrofurantoin pulmonary toxicity: neglected threat
Potential adverse effects include pulmonary toxicity INTRODUCTION: Nitrofurantoin is commonly used to treat urinary tract infections (UTI), and in rare cases, it can lead to pulmonary toxicity with variable presentation
Nitrofurantoin is one of the most common causes of drug induced liver disease and can cause either an acute or a chronic hepatitis-like syndrome that can be severe and lead to
00 + tax (Refund Policy) Nitrofurantoin lung toxicity was diagnosed among ten patients receiving 50 mg/day to prevent recurrent urinary tract infection
Request PDF | Nitrofurantoin-induced pulmonary toxicity: a requirement for regular monitoring | Aims: Medico-legal case reports of hospitalisation for nitrofurantoin-induced pulmonary toxicity Nitrofurantoin lung toxicity was diagnosed among ten patients receiving 50 mg/day to prevent recurrent urinary tract infection
Family Medicine & Medical Science Research Nitrofurantoin pulmonary toxicity: neglected threat