Overview What is aplastic anemia? Aplastic anemia is a rare but serious blood disorder
Most patients with aplastic anemia have pancytopenia, with decreased platelets, white cells, and erythrocytes
Antihypertensive medication use can be associated with a reduction in hemoglobin concentration
Losartan is used alone or together with other medicines to treat high blood pressure (hypertension)
Often, the first test used to diagnose aplastic anemia is a complete blood count (CBC)
Aplastic anemia causes a deficiency of all blood cell types: red blood cells, white
Current Aplastic Anemia Clinical Trials
Aplastic anemia is a disorder in which the cells of the bone marrow that develop into mature blood cells are damaged, leading to low numbers of red blood cells, white blood cells, and/or platelets
Aplastic anemia causes an emergency situation
Acquired aplastic anemia (AA) is a rare, life-threatening bone marrow failure (BMF) disorder that affects patients of all ages and is caused by lymphocyte destruction of early hematopoietic cells
Bone marrow biopsy
Aplastic anemia is a syndrome of bone marrow failure characterized by peripheral pancytopenia and marrow hypoplasia (see the image below)
1 AA confers a significant risk for morbidity and death as a result of its progressivenatural history and/or complications related to suboptimal therapy
The test measures hematocrit, which is the portion of the blood sample made up of red blood cells
The most common of these is Fanconi anaemia
This side effect is most common when you’re first starting losartan or right after your dose is raised
Patients with thymoma usually have full bone marrow recovery following thymectomy
Neutropenia, monocytopenia, and thrombocytopenia, when severe, are Aplastic anemia is a condition that occurs when your body stops producing enough new blood cells
Talk with your doctor about how to cope with these issues
Even though it's referred to as aplastic anemia, it typically presents with pancytopenia, meaning that all three major blood cell lines - the red blood cells, white blood cells, and platelets are affected
Losartan is an angiotensin II receptor blocker (ARB)
1, 2 AA commonly presents at between 15 and 25 years of age, with a second smaller peak after age 60 years