Articles were eligible if they described acute or acute on chronic lamotrigine overdose
The Lamotrigine Blood Level Test is a test to assess the levels of lamotrigine in blood
Lamotrigine is an antiepileptic drug (AED) of the phenyltriazine class that is chemically
Lennox–Gastaut syndrome Lamotrigine is one of a small number of FDA-approved
It is a panel of epilepsy specialist physicians chosen from epilepsy centers belonging to
It is associated with high mortality rates if not recognized early and
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As good pain relief depends on adequate lamotrigine serum concentrations and dangerous side effects should be avoided, we recommend to monitor individual concentration levels in relation to lamotrigine dosage
||Separate serum or plasma from cells ASAP or within 2 hours of collection
Lamotrigine (LTG) is an antiepileptic drug that is metabolized via glucuronidation
The half-life is 25 to 33 hours in adults but decreases with concurrent use of phenytoin or carbamazepine (13-14 hours) and increases with concomitant valproic acid therapy (59-70 hours), kidney The half-life of lamotrigine is perhaps doubled from 30 to 60 hours
The lamotrigine Canadian product monograph states that coadministration of these
0028) between the median daily dose of LMT in children in remission (3
Existing literature indicates that overdose of either drug is typically benign, but neurologic and cardiac toxicity can occur in some cases
For sustained-release formulations only, draw blood a minimum of 12 hours after last dose
Her serum-level-to-dose ratio
Monitoring serum/plasma concentrations of lamotrigine may be useful under certain circumstances
These findings suggest an association between serum level and clinical response
3% of maternal serum concentrations, but unbound infant serum concentrations averaged 30
The target dose of Lamictal is typically 200mg daily Serum sickness — Serum sickness is the prototypic example of the Gell and Coombs "type III" or immune complex-mediated hypersensitivity disease ( table 1) [ 2 ]
5 Most patients were prescribed ≤200 mg/d; however, some were prescribed higher doses
97 showed that there is a slight interaction between lamotrigine and HSA