Phenytoin is classified as an antiarrhythmic and can cause SA and AV nodal blocks as well as dysrhythmias due to its effect on voltage-gated sodium channels
12, 6, 8 Since it's introduction about
Although the recommended therapeutic range is cited to be between 10-20 mg/L
Diphenylhydantoin (Phenytoin) More information about Diphenylhydantoin
Diphenylhydantoin: efficacy, toxicity, and dose-serum level relationships in children
It has also been used as an antidysrhythmic drug
Adjust dose as needed; most adults can be maintained on 300 to 400 mg/day in divided doses
Anticonvulsant
Molecular Weight 274
Phenytoin rút ngắn cơn phóng điện và Phenytoin sodium is a commonly used antiepileptic
Biochem/physiol Actions
Inclusion in an NLM database does not imply endorsement of, or agreement with, the contents by NLM or the National Institutes of diphenylhydantoin: [ fen´ĭ-toin″ ] an anticonvulsant used in the treatment of epilepsy other than the petit mal type, the treatment of status epilepticus , and the prevention and treatment of seizures associated with neurosurgery; administered orally
Screening phenytoin did not reveal comparable sedative side effects as
Molecular Weight 274
The additional usefulness of phenytoin was revealed in 1938 by Tracy Putnam and H
Drug Name
Dosing: Phenytoin or Dilantin (Adults) Status Keywords
Phenytoin (diphenylhydantoin) was the second drug to be synthesized for possible treatment of epilepsy
3) useful in the treatment of epilepsy
5,5-Diphenylhydantoin and its sodium salt are primarily used in the treatment of grand mal and psychomotor seizures, often in combination with other anticonvulsants, including phenobarbital
Phenytoin is slowly but nearly completely absorbed in the small intestine; oral bioavailability ranges from 70 to 100%
Plasma DPH levels fell and on average were some 40 per cent lower at term than they had Phenytoin comes as an extended-release (long-acting) capsule, a chewable tablet, and a suspension (liquid) to take by mouth