In addition, it has been reported that propranolol, another commonly used β-blocker, is likely to exert its protective effect on mitochondrial function in the ischemic heart by attenuating the Propranolol also attenuated ischaemia-induced accumulation in Na+, suggesting that cytosolic sodium overload during ischaemia was prevented by propranolol
The protective effects of ranolazine and propranolol are seemingly due to the prevention of calcium overload and resulting lesions in mitochondria
Mitochondrial profile number and area did not differ
Introduction The possibility that the extent and severity of myocardial ischaemic injury after coronary artery ligation might be altered by certain interventions, has aroused considerable interest
Additionally, chronic propranolol treatment brought about a decrease in the content of cytochrome c + c 1 in heart mitochondria
On the other hand, we showed here the anti-proliferative properties of Prop in various breast cancer cells, in agreement with our previous results in breast carcinoma in The notion that carvedilol is effective in several models of mitochondrial dysfunction, particularly those involving oxidative stress, is supported, as propranolol seems to lack effectiveness in the protection of cardiac mitochondria
Its potential to synergize with certain drugs has been also outlined
Maïlys Rossi