However, the degree of inhibition is small at therapeutic concentrations
Recently, theophylline was found to have several immunomodulatory and anti-inflammatory properties, and thus interest in its use in Side Effects
However, the total dose is usually not more than 20 mg per kg of body weight per day or 600 mg per day
Brand names of this medication are Elixophyllin® and Slo-Phyllin®
It occurs as a white, odorless, crystalline powder with a bitter taste
Elderly: Dose reduction may be necessary
C22 mice show progressive weakness particularly of the hind limbs and an unstable gait The small cohorts served to obtain evidence-based data and to define relevant conditions for a Weight under 45 kg: Initial dose: 12 to 14 mg/kg/day (max 300 mg) given as evenly divided doses every 4 to 6 hours
of sulodexide on both clinical and molecular parameters in patients with mixed arterial and venous ulcers of lower limbs
Thuốc đạn theophylline Following acute overdose, hypokalemia, hyperglycemia, hypercalcemia, hypophosphatemia, and acidosis commonly occur
Adverse effects can occur within the range 10-20 mg/litre and both the Theophylline is structurally classified as a methylxanthine
The molecular formula of anhydrous theophylline is C with a molecular weight of 180
95%CI ‐0
A few of these "thalidomide children" won damages in 1968 and the rest were covered 3
As theophylline (anhydrous) modified-release tab/cap: 6-12 years 20-35 kg: 125-250 mg bid; >12 years Same as adult dose
Cardiovascular symptoms: Hypotension
Pentoxifylline (pen" tox if' i lin) is a small molecular weight methyl derivative of xanthine that appears to act by improving red blood cell deformability, thus reducing blood viscosity as well as decreasing platelet aggregation and thrombus formation
Technical products and impurities
Approximately 10% is excreted unchanged
, bronchodilation) and suppression of the response of the airways to stimuli (i
Although prednisolone can be administered to horses, the small tablet sizes available make it Maintenance dose: 1-<9 years Initially, 0
Because only a small amount of theophylline is eliminated unchanged in the urine (<10% of a dose), dosage adjustments are not necessary in patients with renal impairment
Theophylline in overdose can cause vomiting (which may be severe and intractable), agitation, restlessness, dilated pupils, sinus tachycardia, and hyperglycaemia
Theophylline (thee of' i lin) is a methylxanthine related structurally to caffeine and has been widely used as a bronchodilator since the 1930s
[ 3] Infant serum levels might occasionally accumulate to therapeutic levels in infants In a randomized, double-blind study, 87 preterm neonates with AOP (gestational age of 27-32 weeks) were treated with either theophylline plus 0
The big, bad grand mal seizure is a generalized, convulsive seizure with widespread, excessive, abnormal electrical activity occurring in both sides of the brain
14 The finding from another pilot Theophylline has a narrow or small therapeutic index (TI)
7 mg/kg/hour
Limit your use of caffeine (for example, tea, coffee, cola) and chocolate
Transient tachycardia, irritability and vomiting have been reported in new-borns delivered from mothers consuming theophylline
Such preparations, often with a mild sedative added, dominated the market for oral NOTE: In addition to the factors listed above, theophylline clearance is increased and half-life decreased by low carbohydrate/high protein diets, parenteral nutrition, and daily consumption of charcoal-broiled beef
Theophylline is a multi-purpose medicine which mainly acts as a bronchodilator - in other words, it opens up the air passages in the lungs
, about 10%, of the administered theophylline dose is excreted unchanged in the urine of children greater than three months of age and adults
The main side effects associated with taking theophylline are: General central nervous system stimulation: in very high doses, it can cause nervousness Upper and lower limb reduction defects occur when a part of or the entire arm (upper limb) or leg (lower limb) of a fetus fails to form completely during pregnancy
Gender: Gender differences in theophylline clearance are relatively small and unlikely to be of clinical significance
Theophylline is a weak nonselective inhibitor of phosphodiesterase (PDE) isoenzymes, which break down cyclic nucleotides in the cell, leading to increased
Theophylline is marketed under several
Includes Theophylline indications, dosage/administration, pharmacology, mechanism/onset/duration of action, half
Off Label Uses Bradycardia, heart transplantation
, patients with acute
Final dose: Adjust to maintain peak serum steady state theophylline between 5 to 10 mcg/mL in
Theophylline is structurally classified as a methylxanthine
5–9
A plasma level of 5 micrograms/ml probably represents the lower level of clinical effectiveness
It’s also available in an intravenous (IV) form, which is Buy theo-24 Cr without a prescription
Theophylline stimulates catecholamine release and activates Na + /K +-ATPase
Theophylline base is poorly soluble in water and often results in gastrointestinal irritation when administered orally
Dosage requirement must be guided by the patient’s serum theophylline concentrations, clinical response, lifestyle, and co-morbidities (refer to detailed product guideline)
Các tác dụng khác mà có thể xảy ra ở nồng độ điều trị Child 2–11 years 9 mg/kg every 12 hours (max
Theophylline (ทีโอฟิลลีน) เป็นยาในกลุ่มยารักษาโรคหอบหืด (Antiasthmatic) และโรคปอด มีฤทธิ์คลายกล้ามเนื้อบริเวณรอบ ๆ ทางเดินหายใจภายในปอด ทำให้ทางเดินหายใจ Phocomelia is a rare birth defect
The gastrointestinal transit and absorption of a multiparticulate controlled-release theophylline preparation were investigated under fed and fasted conditions
Gender differences in theophylline clearance are relatively small and unlikely to be of clinical significance
Off Label Uses Bradycardia, heart transplantation
5 Theophylline was prescribed to 35% of patients with COPD in the past and up to 64% in Taiwan because theophylline is convenient to use and inexpensive
If the TI is small (the difference between the two concentrations is very small), the drug must be dosed Maintenance dose: 1-<9 years Initially, 0