feeling tired, and
Rizatriptan is not an inhibitor of the activities of human liver cytochrome P450 isoforms 3A4/5, 2C9, 2C19, or 2E1; however, rizatriptan is a competitive inhibitor (K i =1400 nanoM) of cytochrome P450 2D6, (C max after a 10 mg dose was 74 nanoM)
It is a serotonin (5-HT) 1B/1D receptor agonist (triptan)
, Sumatriptan (Imitrex) works by causing vasoconstriction of cranial vessels, which
Combine with paracetamol, ibuprofen or aspirin as advised
The pain of migraine headaches is thought to be caused by dilated blood vessels inside the
Do not use them to prevent an attack
Rizatriptan – The efficacy of rizatriptan for acute migraine has been demonstrated in a systematic review of multiple randomized placebo-controlled studies
Rizatriptan benzoate is described chemically as: N,N-dimethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-1H indole-3-ethanamine monobenzoate and its structural formula is: Its empirical formula is C15H19N5•C7H6O2, representing a molecular weight of the free base of 269
Rizatriptan’s minimum age is the youngest of all triptans
The likelihood of success appears to be greatest with rizatriptan (10 mg), eletriptan (80 mg), and almotriptan (12
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