It is a cofactor that permits several enzymes to function properly; it plays a role in the immune system; and it is an antioxidant
This happens because removal of an electron from monodehydroascorbate would create a tricarbonyl structure that is Ascorbic acid is an electron donor and acts as a cofactor for fifteen mammalian enzymes
Unlike most mammals and other animals, humans do not have the ability to synthesize vitamin C and must obtain it from the diet
Ascorbic acid or vitamin C is a common enzymatic cofactor in mammals used in the synthesis of collagen
This essential vitamin acts as
Vitamin C (ascorbic acid) is an antioxidant and is involved in the formation of collagen, a protein found in connective tissues
Vitamin C (ascorbic acid) is a cofactor of prolyl-hydroxylases that modify newly synthesized collagen on the route for secretion
Since vitamin C (ascorbic acid) is a cofactor in the inactivation of dopamine-beta-hydroxylase by 4-cresol and HPHPA, vitamin C (ascorbic acid) supplementation and/or
Ascorbic acid is an essential water-soluble vitamin, commonly known as vitamin C
A cofactor is a non- protein chemical compound or metallic ion that is required for an enzyme 's role as a catalyst (a catalyst is a substance that increases the rate of a chemical reaction )
Post-translation hydroxylation of these residues increases the degree of intra-molecular cross-linking of collagen and elastin and facilitates the Ascorbic acid (AsA), which is a cofactor for a variety of enzymes and has an antioxidant effect, cannot be synthesized by certain animals, including humans
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The only patients to recover were those who received lemons and oranges, but almost 200 years would pass before the curative compound was identified as hexuronic acid, later named ascorbic acid (ascorbate) for its anti-scorbutic (i
This essential vitamin acts as a cofactor to the mixed-function Since AsA is a co-factor required for the biosynthesis of gibberellins, ethylene and abscisic acid (Barth et al
l-Ascorbic acid (AA), generally known as vitamin C, is a crucial cofactor for a variety of enzymes, including prolyl-3-hydroxylase (P3H), prolyl-4-hydroxylase (P4H), and lysyl hydroxylase (LH)-mediated collagen maturation
This review focuses on the role of ascorbate in
It is not synthesized in humans and some other animal species and has to be provided by diet or pharmacologic means
It is actively imported into the endoplasmic reticulum of cells via glucose transporters
In addition to its antioxidant function, vitamin C is also a cofactor for a number of enzymes or Some biochemical functions of vitamin C make it an essential component of parenteral nutrition (PN) and an important therapeutic supplement in other acute conditions
As an electron donor, ascorbic acid can keep iron in the ferrous state, thereby maintaining the full activity of collagen hydroxylase