Printable Drug Interactions Close all Moderate Xanax + Gabapentin The following applies to the ingredients: Alprazolam (found in Xanax) and Gabapentin Using ALPRAZolam together with gabapentin may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. [10] Alprazolam is most commonly used in management of anxiety disorders, specifically panic disorder or generalized anxiety disorder (GAD)